NIOD Copper Amino Isolate Serum 3 1:1 Review

NIOD Copper Amino Isolate Serum 3 1:1 review


If you’re a loyal fan of the best-selling, multi-awarding-winning NIOD Copper Amino Isolate Serum, then this is the perfect read for you as I’ll be filling you in on the 2022 update of this fan-favourite anti-ageing serum with the 3 1:1 edition…


The Most Important Thing About This Serum Is…

As the numerical name suggests, this is the third generation of NIOD’s iconic Copper Amino Isolate Serum as it replaces the Copper Amino Isolate Serum 2:1 version. The formula now comes in just one apothecary-style glass bottle, but the formulation itself is just as impressive. And yes, it’s still blue!

You might expect this youthful-restoring serum to target signs of ageing directly, but it adopts a novel approach indirectly targeting ageing. It does this by abandoning the traditional approach of addressing visible skin ageing; instead, it emphasises creating a foundation to respect skin health. The thinking behind this is healthy skin equals happy, youthful skin.


What Skin Type Is It For?

This serum is specially designed for skin experiencing signs of ageing.


You Will Love This If…

If you loved the previous version of the NIOD serum, then you’ll adore this version; it’s even better, and it’s much easier to use.


Hero Ingredients:

The previous generation of the Copper Amino Isolate Serum (let’s call it CAIS for short) contained 2% of pure GHK peptide, but you had to mix two formulas to get the total 2% dose. The updated formula has scrapped the need for mixing (and cuts excess waste) as the new serum features a 1% dose of pre-assembled and fully stable GHK-Cu alongside a 1% GHK peptide. These clever (albeit slightly complex) actives improve tissue repair, increase collagen and boost elastin – healthy skin essentials! But that’s not all; the 2% concentration of GHK and GHK-Cu helps to improve textural irregularities and uneven tone while shrinking pores and boosting radiance.

The serum also features several additional collagen-supporting peptides and skin-hydrating hyaluronic acid for a plump, firm, bouncy complexion. As this is NIOD that we’re talking about, there are yet more actives to come: advanced 100% plant-based mono-dispersed glycogen protects the formulation peptides but break upon application so that the serum can get to work on your skin. At the same time, a form of lipo-oligopeptide supports healthy skin renewal.


What Does It Feel Like?

The serum has a water-like liquid texture that glides into your skin and sinks into your skin in seconds, so it doesn’t feel heavy or sticky. It’s very runny, so take care to avoid waste when applying!


What Does It Smell Like?

The serum has a light medicinal, almost vinegar-like scent, but it’s not noticeable when you’ve applied it to your skin.


How Do You Use The Product?

Apply to clean, dry skin both morning and evening, before the application of thicker serums or creams.


What’s Special About The Design?

If you were a fan of the NIOD Copper Amino Isolate Serum 2 1:1, then the chances are that you’ll love the 2022 design update. Yes, the fact that you had to mix the serum with an activator was fun, but let’s be honest, it could be a little bit messy too. Thankfully, NIOD have found a way to keep their formula just as active and hardworking as before, while cutting out the need for an activator; this sleek pipette-topped bottle has everything you need in just one bottle. No need for mixing (or excess packaging) here.




Alcohol-free, oil-free, silicone-free, nut-free, gluten-free, cruelty-free.


More from NIOD

Your Guide To NIOD Skincare

6 Products To Use If Your Main Skincare Concern Is Pores

Shop this post